Bone Marrow Macrophages Induce Inflammation by Efferocytosis of Apoptotic Prostate Cancer Cells via HIF-1α Stabilization

The clearance of apoptotic cancer cells by macrophages, known as efferocytosis, fuels the bone-metastatic growth of prostate cancer cells via pro-inflammatory and immunosuppressive processes. However, the exact molecular mechanisms remain unclear. In this study, single-cell transcriptomics of bone m...

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Detalles Bibliográficos
Autores principales: Mendoza-Reinoso, Veronica, Schnepp, Patricia M., Baek, Dah Youn, Rubin, John R., Schipani, Ernestina, Keller, Evan T., McCauley, Laurie K., Roca, Hernan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737180/
https://www.ncbi.nlm.nih.gov/pubmed/36496973
http://dx.doi.org/10.3390/cells11233712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737180/
https://www.ncbi.nlm.nih.gov/pubmed/36496973
http://dx.doi.org/10.3390/cells11233712

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