Similarity-Based Virtual Screening to Find Antituberculosis Agents Based on Novel Scaffolds: Design, Syntheses and Pharmacological Assays

A method to identify molecular scaffolds potentially active against the Mycobacterium tuberculosis complex (MTBC) is developed. A set of structurally heterogeneous agents against MTBC was used to obtain a mathematical model based on topological descriptors. This model was statistically validated thr...

Descripción completa

Detalles Bibliográficos
Autores principales: García-García, Ángela, de Julián-Ortiz, Jesus Vicente, Gálvez, Jorge, Font, David, Ayats, Carles, Guna Serrano, María del Remedio, Muñoz-Collado, Carlos, Borrás, Rafael, Villalgordo, José Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737236/
https://www.ncbi.nlm.nih.gov/pubmed/36499384
http://dx.doi.org/10.3390/ijms232315057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737236/
https://www.ncbi.nlm.nih.gov/pubmed/36499384
http://dx.doi.org/10.3390/ijms232315057

Ejemplares similares