Novel Dual AChE and ROCK2 Inhibitor Induces Neurogenesis via PTEN/AKT Pathway in Alzheimer’s Disease Model

Alzheimer’s disease (AD) is a progressive and complex neurodegenerative disease. Acetylcholinesterase inhibitors (AChEIs) are a major class of drugs used in AD therapy. ROCK2, another promising target for AD, has been associated with the induction of neurogenesis via PTEN/AKT. This study aimed to ch...

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Detalles Bibliográficos
Autores principales: Moreira, Natália Chermont dos Santos, Tamarozzi, Elvira Regina, Lima, Jessica Ellen Barbosa de Freitas, Piassi, Larissa de Oliveira, Carvalho, Ivone, Passos, Geraldo Aleixo, Sakamoto-Hojo, Elza Tiemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737254/
https://www.ncbi.nlm.nih.gov/pubmed/36499116
http://dx.doi.org/10.3390/ijms232314788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737254/
https://www.ncbi.nlm.nih.gov/pubmed/36499116
http://dx.doi.org/10.3390/ijms232314788

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