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Discovery of 5-Methylthiazole-Thiazolidinone Conjugates as Potential Anti-Inflammatory Agents: Molecular Target Identification and In Silico Studies

A series of previously synthesized 5-benzyliden-2-(5-methylthiazole-2-ylimino)thiazoli- din-4-one were evaluated for their anti-inflammatory activity on the basis of PASS predictive outcomes. The predictive compounds were found to demonstrate moderate to good anti-inflammatory activity, and some of...

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Detalles Bibliográficos
Autores principales: Haroun, Michelyne, Petrou, Anthi, Tratrat, Christophe, Kolokotroni, Aggeliki, Fesatidou, Maria, Zagaliotis, Panagiotis, Gavalas, Antonis, Venugopala, Katharigatta N., Sreeharsha, Nagaraja, Nair, Anroop B., Elsewedy, Heba Sadek, Geronikaki, Athina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737349/
https://www.ncbi.nlm.nih.gov/pubmed/36500230
http://dx.doi.org/10.3390/molecules27238137