Dual-Specificity Protein Phosphatase 4 (DUSP4) Overexpression Improves Learning Behavior Selectively in Female 5xFAD Mice, and Reduces β-Amyloid Load in Males and Females

Recent multiscale network analyses of banked brains from subjects who died of late-onset sporadic Alzheimer’s disease converged on VGF (non-acronymic) as a key hub or driver. Within this computational VGF network, we identified the dual-specificity protein phosphatase 4 (DUSP4) [also known as mitoge...

Descripción completa

Detalles Bibliográficos
Autores principales: Pan, Allen L., Audrain, Mickael, Sakakibara, Emmy, Joshi, Rajeev, Zhu, Xiaodong, Wang, Qian, Wang, Minghui, Beckmann, Noam D., Schadt, Eric E., Gandy, Sam, Zhang, Bin, Ehrlich, Michelle E., Salton, Stephen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737364/
https://www.ncbi.nlm.nih.gov/pubmed/36497141
http://dx.doi.org/10.3390/cells11233880

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737364/
https://www.ncbi.nlm.nih.gov/pubmed/36497141
http://dx.doi.org/10.3390/cells11233880

Ejemplares similares