MgADP Promotes Myosin Head Movement toward Actin at Low [Ca(2+)] to Increase Force Production and Ca(2+)-Sensitivity of Contraction in Permeabilized Porcine Myocardial Strips

Myosin cross-bridges dissociate from actin following Mg(2+)-adenosine triphosphate (MgATP) binding. Myosin hydrolyses MgATP into inorganic phosphate (P(i)) and Mg(2+)-adenosine diphosphate (ADP), and release of these hydrolysis products drives chemo-mechanical energy transitions within the cross-bri...

Descripción completa

Detalles Bibliográficos
Autores principales: Awinda, Peter O., Ma, Weikang, Turner, Kyrah L., Zhao, Jing, Gong, Henry, Thompson, Mindy S., Campbell, Kenneth S., Irving, Thomas C., Tanner, Bertrand C. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737397/
https://www.ncbi.nlm.nih.gov/pubmed/36499408
http://dx.doi.org/10.3390/ijms232315084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737397/
https://www.ncbi.nlm.nih.gov/pubmed/36499408
http://dx.doi.org/10.3390/ijms232315084

Ejemplares similares