Preventing Surgery-Induced NK Cell Dysfunction Using Anti-TGF-β Immunotherapeutics

Natural Killer (NK) cell cytotoxicity and interferon-gamma (IFNγ) production are profoundly suppressed postoperatively. This dysfunction is associated with increased morbidity and cancer recurrence. NK activity depends on the integration of activating and inhibitory signals, which may be modulated b...

Descripción completa

Detalles Bibliográficos
Autores principales: Market, Marisa, Tennakoon, Gayashan, Scaffidi, Marlena, Cook, David P., Angka, Leonard, Ng, Juliana, Tanese de Souza, Christiano, Kennedy, Michael A., Vanderhyden, Barbara C., Auer, Rebecca C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737532/
https://www.ncbi.nlm.nih.gov/pubmed/36498937
http://dx.doi.org/10.3390/ijms232314608

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737532/
https://www.ncbi.nlm.nih.gov/pubmed/36498937
http://dx.doi.org/10.3390/ijms232314608

Ejemplares similares