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Preventing Surgery-Induced NK Cell Dysfunction Using Anti-TGF-β Immunotherapeutics
Natural Killer (NK) cell cytotoxicity and interferon-gamma (IFNγ) production are profoundly suppressed postoperatively. This dysfunction is associated with increased morbidity and cancer recurrence. NK activity depends on the integration of activating and inhibitory signals, which may be modulated b...
Autores principales: | Market, Marisa, Tennakoon, Gayashan, Scaffidi, Marlena, Cook, David P., Angka, Leonard, Ng, Juliana, Tanese de Souza, Christiano, Kennedy, Michael A., Vanderhyden, Barbara C., Auer, Rebecca C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737532/ https://www.ncbi.nlm.nih.gov/pubmed/36498937 http://dx.doi.org/10.3390/ijms232314608 |
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