Longevity-Associated Variant of BPIFB4 Confers Neuroprotection in the STHdh Cell Model of Huntington Disease

Huntington’s disease (HD) is caused by the production of mutant Huntingtin (mHTT), characterized by long polyglutamine repeats with toxic effects. There are currently no clinically validated therapeutic agents that slow or halt HD progression, resulting in a significant clinical unmet need. The stri...

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Detalles Bibliográficos
Autores principales: Cattaneo, Monica, Maciag, Anna, Milella, Maria Serena, Ciaglia, Elena, Bruno, Antonino, Puca, Annibale Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737551/
https://www.ncbi.nlm.nih.gov/pubmed/36499641
http://dx.doi.org/10.3390/ijms232315313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737551/
https://www.ncbi.nlm.nih.gov/pubmed/36499641
http://dx.doi.org/10.3390/ijms232315313

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