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Inhibitory Effects of Varespladib, CP471474, and Their Potential Synergistic Activity on Bothrops asper and Crotalus durissus cumanensis Venoms

Snakebite is a neglected tropical disease that causes extensive mortality and morbidity in rural communities. Antivenim sera are the currently approved therapy for snake bites; however, they have some therapeutic limitations that have been extensively documented. Recently, small molecule toxin inhib...

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Detalles Bibliográficos
Autores principales: Quiroz, Sara, Henao Castañeda, Isabel C., Granados, Johan, Patiño, Arley Camilo, Preciado, Lina María, Pereañez, Jaime Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737558/
https://www.ncbi.nlm.nih.gov/pubmed/36500682
http://dx.doi.org/10.3390/molecules27238588