Animal Welfare Considerations When Conducting OECD Test Guideline Inhalation and Toxicokinetic Studies for Nanomaterials

SIMPLE SUMMARY: Animal welfare considerations with the 3R principles, Replacement, Reduction, and Refinement (3Rs), have become more important in regulatory toxicity testing. Modifying OECD inhalation toxicity test guidelines 412 and 413 aim to minimize animal use and maximize the number of endpoint...

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Detalles Bibliográficos
Autores principales: Chung, Yong Hyun, Gulumian, Mary, Pleus, Richard C., Yu, Il Je
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737563/
https://www.ncbi.nlm.nih.gov/pubmed/36496826
http://dx.doi.org/10.3390/ani12233305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737563/
https://www.ncbi.nlm.nih.gov/pubmed/36496826
http://dx.doi.org/10.3390/ani12233305

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