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Animal Welfare Considerations When Conducting OECD Test Guideline Inhalation and Toxicokinetic Studies for Nanomaterials
SIMPLE SUMMARY: Animal welfare considerations with the 3R principles, Replacement, Reduction, and Refinement (3Rs), have become more important in regulatory toxicity testing. Modifying OECD inhalation toxicity test guidelines 412 and 413 aim to minimize animal use and maximize the number of endpoint...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737563/ https://www.ncbi.nlm.nih.gov/pubmed/36496826 http://dx.doi.org/10.3390/ani12233305 |