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Combined Effects of Lycopene and Metformin on Decreasing Oxidative Stress by Triggering Endogenous Antioxidant Defenses in Diet-Induced Obese Mice

Since lycopene has antioxidant activity, its combination with metformin may be useful to contrast diabetic complications related to oxidative stress. This study aimed to investigate the effects of metformin combined with lycopene on high-fat diet (HFD)-induced obese mice. Seventy-two C57BL-6J mice w...

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Detalles Bibliográficos
Autores principales: Motta, Bruno Pereira, Pinheiro, Camila Graça, Figueiredo, Ingrid Delbone, Cardoso, Felipe Nunes, Oliveira, Juliana Oriel, Machado, Rachel Temperani Amaral, da Silva, Patrícia Bento, Chorilli, Marlus, Brunetti, Iguatemy Lourenço, Baviera, Amanda Martins
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737677/
https://www.ncbi.nlm.nih.gov/pubmed/36500596
http://dx.doi.org/10.3390/molecules27238503