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Evaluation of a Novel Oncolytic Adenovirus Silencing SYVN1

Oncolytic adenoviruses are promising new anticancer agents. To realize their full anticancer potential, they are being engineered to express therapeutic payloads. Tumor suppressor p53 function contributes to oncolytic adenovirus activity. Many cancer cells carry an intact TP53 gene but express p53 i...

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Detalles Bibliográficos
Autores principales: Vermeulen, Christie, Brachtlova, Tereza, Tol, Nikki, van der Meulen-Muileman, Ida H., Hodzic, Jasmina, van de Vrugt, Henri J., van Beusechem, Victor W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737683/
https://www.ncbi.nlm.nih.gov/pubmed/36499754
http://dx.doi.org/10.3390/ijms232315430