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A Hydrodistillate of Gynostemma pentaphyllum and Damulin B Prevent Cisplatin-Induced Nephrotoxicity In Vitro and In Vivo via Regulation of AMPKα1 Transcription

The clinical application of cisplatin, one of the most effective chemotherapeutic agents used to treat various cancers, has been limited by the risk of adverse effects, notably nephrotoxicity. Despite intensive research for decades, there are no effective approaches for alleviating cisplatin nephrot...

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Detalles Bibliográficos
Autores principales: Song, Minhyeok, Kim, Minseok, Hoang, Dang Hieu, Kovale, Lochana Mangesh, Lee, Jihyun, Kim, Youngjoo, Lee, Changhyun, Hong, Jongki, Park, Sungchul, Choe, Wonchae, Kang, Insug, Kim, Sung Soo, Ha, Joohun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737728/
https://www.ncbi.nlm.nih.gov/pubmed/36501027
http://dx.doi.org/10.3390/nu14234997