A Novel Method to Construct 2-Aminobenzofurans via [4 + 1] Cycloaddition Reaction of In Situ Generated Ortho-Quinone Methides with Isocyanides

A new approach for the synthesis of 2-aminobenzofurans has been described via Sc(OTf)(3) mediated formal cycloaddition of isocyanides with the in situ generated ortho-quinone methides (o-QMs) from o-hydroxybenzhydryl alcohol. Notably, as a class of readily available and highly active intermediates,...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Huaxin, Tang, Senling, Pan, Yang, Liang, Peng, Ma, Xiaofeng, Jiao, Wei, Shao, Huawu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737762/
https://www.ncbi.nlm.nih.gov/pubmed/36500630
http://dx.doi.org/10.3390/molecules27238538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737762/
https://www.ncbi.nlm.nih.gov/pubmed/36500630
http://dx.doi.org/10.3390/molecules27238538

Ejemplares similares