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A Novel Method to Construct 2-Aminobenzofurans via [4 + 1] Cycloaddition Reaction of In Situ Generated Ortho-Quinone Methides with Isocyanides

A new approach for the synthesis of 2-aminobenzofurans has been described via Sc(OTf)(3) mediated formal cycloaddition of isocyanides with the in situ generated ortho-quinone methides (o-QMs) from o-hydroxybenzhydryl alcohol. Notably, as a class of readily available and highly active intermediates,...

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Detalles Bibliográficos
Autores principales:	Lin, Huaxin, Tang, Senling, Pan, Yang, Liang, Peng, Ma, Xiaofeng, Jiao, Wei, Shao, Huawu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737762/ https://www.ncbi.nlm.nih.gov/pubmed/36500630 http://dx.doi.org/10.3390/molecules27238538

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