Response Surface Methodology (RSM) Powered Formulation Development, Optimization and Evaluation of Thiolated Based Mucoadhesive Nanocrystals for Local Delivery of Simvastatin

In oral administration systems, mucoadhesive polymers are crucial for drug localization and target-specific activities. The current work focuses on the application of thiolated xanthan gum (TXG) to develop and characterize a novel mucoadhesive nanocrystal (NC) system of simvastatin (SIM). Preparatio...

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Detalles Bibliográficos
Autores principales: Bakhaidar, Rana B., Naveen, Nimbagal Raghavendra, Basim, Pratap, Murshid, Samar S., Kurakula, Mallesh, Alamoudi, Abdulmohsin J., Bukhary, Deena M., Jali, Abdulmajeed M., Majrashi, Mohammed A., Alshehri, Sameer, Alissa, Mohammed, Ahmed, Rayan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737842/
https://www.ncbi.nlm.nih.gov/pubmed/36501579
http://dx.doi.org/10.3390/polym14235184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737842/
https://www.ncbi.nlm.nih.gov/pubmed/36501579
http://dx.doi.org/10.3390/polym14235184

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