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Pro- and Anti-Tumoral Factors Involved in Total Body Irradiation and Interleukin-2 Conditioning in Adoptive T Cell Therapy of Melanoma-Bearing Rag1 Knock-Out Mice

In adoptive T cell therapy (ACT), the transfer of tumor-specific T cells is paralleled by the conditioning regimen to increase therapeutic efficacy. Pre-conditioning depletes immune-suppressive cells and post-conditioning increases homeostatic signals to improve the persistence of administered T cel...

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Detalles Bibliográficos
Autores principales: Kim, Seon-Hee, Go, Eun Mi, Shin, Dong Hoon, Choi, Beom K., Han, Chungyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737859/
https://www.ncbi.nlm.nih.gov/pubmed/36497152
http://dx.doi.org/10.3390/cells11233894