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The Efficacy of HGF/VEGF Gene Therapy for Limb Ischemia in Mice with Impaired Glucose Tolerance: Shift from Angiogenesis to Axonal Growth and Oxidative Potential in Skeletal Muscle

Background: Combined non-viral gene therapy (GT) of ischemia and cardiovascular disease is a promising tool for potential clinical translation. In previous studies our group has developed combined gene therapy by vascular endothelial growth factor 165 (VEGF165) + hepatocyte growth factor (HGF). Our...

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Detalles Bibliográficos
Autores principales: Stafeev I, Iurii S., Boldyreva, Maria A., Michurina, Svetlana S., Agareva, Margarita Yu., Radnaeva, Arina V., Menshikov, Mikhail Yu., Hu, Yu-Chen, Makarevich, Pavel I., Parfyonova, Yelena V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737863/
https://www.ncbi.nlm.nih.gov/pubmed/36497083
http://dx.doi.org/10.3390/cells11233824