Neomycin, but Not Neamine, Blocks Angiogenic Factor Induced Nitric Oxide Release through Inhibition of Akt Phosphorylation

Angiogenesis, the growth of new blood vessels, is a critical factor of carcinogenesis. Neomycin and neamine, two drugs blocking the nuclear translocation of angiogenin (ANG), have been proven to inhibit tumour growth in vivo. However, the high toxicity of neomycin prevents its therapeutic use, thus...

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Detalles Bibliográficos
Autores principales: Trouillon, Raphaël, Kang, Dong-Ku, Chang, Soo-Ik, O’Hare, Danny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737909/
https://www.ncbi.nlm.nih.gov/pubmed/36499606
http://dx.doi.org/10.3390/ijms232315277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737909/
https://www.ncbi.nlm.nih.gov/pubmed/36499606
http://dx.doi.org/10.3390/ijms232315277

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