The Aurora Kinase Inhibitor TAK901 Inhibits Glioblastoma Growth by Blocking SREBP1-Mediated Lipid Metabolism

SIMPLE SUMMARY: Glioblastoma (GBM) is the most common and aggressive malignant primary brain tumor. However, the therapeutic efficacy for GBM remains unsatisfactory. In this study, we found that TAK901, an Aurora kinase inhibitor, reduced the cell viability of both the GBM cell line and glioma stem...

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Detalles Bibliográficos
Autores principales: Zhan, Xiudan, Qiu, Ru, He, Yi, Zhao, Zijin, Huang, Meng, Liu, Qing, Zhi, Feng, Long, Wenyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737940/
https://www.ncbi.nlm.nih.gov/pubmed/36497287
http://dx.doi.org/10.3390/cancers14235805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737940/
https://www.ncbi.nlm.nih.gov/pubmed/36497287
http://dx.doi.org/10.3390/cancers14235805

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