The Cytotoxic Effects of Cannabidiol and Cannabigerol on Glioblastoma Stem Cells May Mostly Involve GPR55 and TRPV1 Signalling

SIMPLE SUMMARY: In glioblastoma (GBM), the highest-grade IV glioma, members of the large membrane receptor family of G protein-coupled receptors (GPCRs) are upregulated including CB1 and GPR55 that along with non-selective ion transporter protein TRPV1 bind endocannabinoids and phytocannabinoids wit...

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Detalles Bibliográficos
Autores principales: Lah, Tamara T., Majc, Bernarda, Novak, Metka, Sušnik, Ajda, Breznik, Barbara, Porčnik, Andrej, Bošnjak, Roman, Sadikov, Aleksander, Malavolta, Marta, Halilčević, Selma, Mlakar, Jernej, Zomer, Roby
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738061/
https://www.ncbi.nlm.nih.gov/pubmed/36497400
http://dx.doi.org/10.3390/cancers14235918

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738061/
https://www.ncbi.nlm.nih.gov/pubmed/36497400
http://dx.doi.org/10.3390/cancers14235918

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