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Caerin 1.1/1.9 Enhances Antitumour Immunity by Activating the IFN-α Response Signalling Pathway of Tumour Macrophages

SIMPLE SUMMARY: Cancer immunotherapy has been enabled by immune checkpoint blockade, but is ineffective in many patients, mainly due to the high complexity of the immune-suppressive tumour microenvironment (TME). Here, with a murine transplantable tumour model, we demonstrate that host-defence caeri...

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Detalles Bibliográficos
Autores principales: Yang, Xiaodan, Liu, Xiaosong, Li, Junjie, Zhang, Pingping, Li, Hejie, Chen, Guoqiang, Zhang, Wei, Wang, Tianfang, Frazer, Ian, Ni, Guoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738106/
https://www.ncbi.nlm.nih.gov/pubmed/36497272
http://dx.doi.org/10.3390/cancers14235785