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New Nucleic Base-Tethered Trithiolato-Bridged Dinuclear Ruthenium(II)-Arene Compounds: Synthesis and Antiparasitic Activity

Aiming toward compounds with improved anti-Toxoplasma activity by exploiting the parasite auxotrophies, a library of nucleobase-tethered trithiolato-bridged dinuclear ruthenium(II)-arene conjugates was synthesized and evaluated. Structural features such as the type of nucleobase and linking unit wer...

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Detalles Bibliográficos
Autores principales: Desiatkina, Oksana, Mösching, Martin, Anghel, Nicoleta, Boubaker, Ghalia, Amdouni, Yosra, Hemphill, Andrew, Furrer, Julien, Păunescu, Emilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738179/
https://www.ncbi.nlm.nih.gov/pubmed/36500266
http://dx.doi.org/10.3390/molecules27238173