Acetylation State of Lysine 14 of Histone H3.3 Affects Mutant Huntingtin Induced Pathogenesis

Huntington’s Disease (HD) is a fatal neurodegenerative disorder caused by the expansion of a polyglutamine-coding CAG repeat in the Huntingtin gene. One of the main causes of neurodegeneration in HD is transcriptional dysregulation that, in part, is caused by the inhibition of histone acetyltransfer...

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Detalles Bibliográficos
Autores principales: Faragó, Anikó, Zsindely, Nóra, Farkas, Anita, Neller, Alexandra, Siági, Fruzsina, Szabó, Márton Richárd, Csont, Tamás, Bodai, László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738228/
https://www.ncbi.nlm.nih.gov/pubmed/36499499
http://dx.doi.org/10.3390/ijms232315173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738228/
https://www.ncbi.nlm.nih.gov/pubmed/36499499
http://dx.doi.org/10.3390/ijms232315173

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