SRSF3 and HNRNPH1 Regulate Radiation-Induced Alternative Splicing of Protein Arginine Methyltransferase 5 in Hepatocellular Carcinoma

Protein arginine methyltransferase 5 (PRMT5) is an epigenetic regulator which has been proven to be a potential target for cancer therapy. We observed that PRMT5 underwent alternative splicing (AS) and generated a spliced isoform PRMT5-ISO5 in hepatocellular carcinoma (HCC) patients after radiothera...

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Detalles Bibliográficos
Autores principales: Wen, Chaowei, Tian, Zhujun, Li, Lan, Chen, Tongke, Chen, Huajian, Dai, Jichen, Liang, Zhenzhen, Ma, Shumei, Liu, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738276/
https://www.ncbi.nlm.nih.gov/pubmed/36499164
http://dx.doi.org/10.3390/ijms232314832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738276/
https://www.ncbi.nlm.nih.gov/pubmed/36499164
http://dx.doi.org/10.3390/ijms232314832

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