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Genomewide m(6)A Mapping Uncovers Dynamic Changes in the m(6)A Epitranscriptome of Cisplatin-Treated Apoptotic HeLa Cells

Cisplatin (CP), which is a conventional cancer chemotherapeutic drug, induces apoptosis by modulating a diverse array of gene regulatory mechanisms. However, cisplatin-mediated changes in the m(6)A methylome are unknown. We employed an m(6)A miCLIP-seq approach to investigate the effect of m(6)A met...

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Detalles Bibliográficos
Autores principales: Alasar, Azime Akçaöz, Tüncel, Özge, Gelmez, Ayşe Bengisu, Sağlam, Buket, Vatansever, İpek Erdoğan, Akgül, Bünyamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738315/
https://www.ncbi.nlm.nih.gov/pubmed/36497162
http://dx.doi.org/10.3390/cells11233905