Nicotinamide Mononucleotide Supplementation Improves Mitochondrial Dysfunction and Rescues Cellular Senescence by NAD(+)/Sirt3 Pathway in Mesenchymal Stem Cells

In vitro expansion-mediated replicative senescence has severely limited the clinical applications of mesenchymal stem cells (MSCs). Accumulating studies manifested that nicotinamide adenine dinucleotide (NAD(+)) depletion is closely related to stem cell senescence and mitochondrial metabolism disord...

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Detalles Bibliográficos
Autores principales: Wang, Huan, Sun, Yanan, Pi, Chenchen, Yu, Xiao, Gao, Xingyu, Zhang, Chang, Sun, Hui, Zhang, Haiying, Shi, Yingai, He, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738479/
https://www.ncbi.nlm.nih.gov/pubmed/36499074
http://dx.doi.org/10.3390/ijms232314739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738479/
https://www.ncbi.nlm.nih.gov/pubmed/36499074
http://dx.doi.org/10.3390/ijms232314739

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