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Efficacy of Clinically Used PARP Inhibitors in a Murine Model of Acute Lung Injury

Poly(ADP-ribose) polymerase 1 (PARP1), as a potential target for the experimental therapy of acute lung injury (ALI), was identified over 20 years ago. However, clinical translation of this concept was not possible due to the lack of clinically useful PARP inhibitors. With the clinical introduction...

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Detalles Bibliográficos
Autores principales: Martins, Vanessa, Santos, Sidneia S., Rodrigues, Larissa de O. C. P., Salomao, Reinaldo, Liaudet, Lucas, Szabo, Csaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738530/
https://www.ncbi.nlm.nih.gov/pubmed/36497049
http://dx.doi.org/10.3390/cells11233789