Dissection of Functional Domains of Orc1-2, the Archaeal Global DNA Damage-Responsive Regulator

Orc1-2 is a non-initiator ortholog of archaeal/eukaryotic Orc1 proteins, which functions as a global regulator in DNA damage-responsive (DDR) expression. As for Orc1 initiators, the DDR regulator harbors an AAA+ ATPase domain, an Initiator-Specific Motif (ISM) and a winged-helix (wH) DNA-binding dom...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Xiaotong, Sun, Mengmeng, Xu, Ruyi, Shen, Yulong, Huang, Qihong, Feng, Xu, She, Qunxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738581/
https://www.ncbi.nlm.nih.gov/pubmed/36498936
http://dx.doi.org/10.3390/ijms232314609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738581/
https://www.ncbi.nlm.nih.gov/pubmed/36498936
http://dx.doi.org/10.3390/ijms232314609

Ejemplares similares