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Dissection of Functional Domains of Orc1-2, the Archaeal Global DNA Damage-Responsive Regulator
Orc1-2 is a non-initiator ortholog of archaeal/eukaryotic Orc1 proteins, which functions as a global regulator in DNA damage-responsive (DDR) expression. As for Orc1 initiators, the DDR regulator harbors an AAA+ ATPase domain, an Initiator-Specific Motif (ISM) and a winged-helix (wH) DNA-binding dom...
Autores principales: | Liu, Xiaotong, Sun, Mengmeng, Xu, Ruyi, Shen, Yulong, Huang, Qihong, Feng, Xu, She, Qunxin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738581/ https://www.ncbi.nlm.nih.gov/pubmed/36498936 http://dx.doi.org/10.3390/ijms232314609 |
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