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SnSe Nanosheets Mimic Lactate Dehydrogenase to Reverse Tumor Acid Microenvironment Metabolism for Enhancement of Tumor Therapy

The acidic tumor microenvironment (TME) is unfriendly to the activity and function of immune cells in the TME. Here, we report inorganic nanozymes (i.e., SnSe NSs) that mimic the catalytic activity of lactate dehydrogenase to degrade lactate to pyruvate, contributing to the metabolic treatment of tu...

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Detalles Bibliográficos
Autores principales: Wang, Heng, Wang, Beilei, Jiang, Jie, Wu, Yi, Song, Anning, Wang, Xiaoyu, Yao, Chenlu, Dai, Huaxing, Xu, Jialu, Zhang, Yue, Ma, Qingle, Xu, Fang, Li, Ruibin, Wang, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738583/
https://www.ncbi.nlm.nih.gov/pubmed/36500643
http://dx.doi.org/10.3390/molecules27238552