N-[1,3-Dialkyl(aryl)-2-oxoimidazolidin-4-ylidene]-aryl(alkyl)sulphonamides as Novel Selective Human Cannabinoid Type 2 Receptor (hCB2R) Ligands; Insights into the Mechanism of Receptor Activation/Deactivation

Cannabinoid type 1 (hCB1) and type 2 (hCB2) receptors are pleiotropic and crucial targets whose signaling contributes to physiological homeostasis and its restoration after injury. Being predominantly expressed in peripheral tissues, hCB2R represents a safer therapeutic target than hCB1R, which is h...

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Detalles Bibliográficos
Autores principales: Gianquinto, Eleonora, Sodano, Federica, Rolando, Barbara, Kostrzewa, Magdalena, Allarà, Marco, Mahmoud, Ali Mokhtar, Kumar, Poulami, Spyrakis, Francesca, Ligresti, Alessia, Chegaev, Konstantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738591/
https://www.ncbi.nlm.nih.gov/pubmed/36500256
http://dx.doi.org/10.3390/molecules27238152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738591/
https://www.ncbi.nlm.nih.gov/pubmed/36500256
http://dx.doi.org/10.3390/molecules27238152

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