HPLC with Fluorescence and Photodiode Array Detection for Quantifying Capmatinib in Biological Samples: Application to In Vivo and In Vitro Studies

Capmatinib, a recently approved tyrosine kinase inhibitor, is used for the treatment of non-small cell lung cancer. We describe two new HPLC methods for capmatinib quantification in vivo and in vitro. HPLC with a fluorescence detection method was used to quantify capmatinib in plasma for the first t...

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Detalles Bibliográficos
Autores principales: Zayed, Aref, Jaber, Sana’a A., Al Hroot, Jomana, Hawamdeh, Sahar, Ayoub, Nehad M., Qinna, Nidal A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738601/
https://www.ncbi.nlm.nih.gov/pubmed/36500674
http://dx.doi.org/10.3390/molecules27238582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738601/
https://www.ncbi.nlm.nih.gov/pubmed/36500674
http://dx.doi.org/10.3390/molecules27238582

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