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HPLC with Fluorescence and Photodiode Array Detection for Quantifying Capmatinib in Biological Samples: Application to In Vivo and In Vitro Studies
Capmatinib, a recently approved tyrosine kinase inhibitor, is used for the treatment of non-small cell lung cancer. We describe two new HPLC methods for capmatinib quantification in vivo and in vitro. HPLC with a fluorescence detection method was used to quantify capmatinib in plasma for the first t...
Autores principales: | Zayed, Aref, Jaber, Sana’a A., Al Hroot, Jomana, Hawamdeh, Sahar, Ayoub, Nehad M., Qinna, Nidal A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738601/ https://www.ncbi.nlm.nih.gov/pubmed/36500674 http://dx.doi.org/10.3390/molecules27238582 |
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