Computer- and NMR-Aided Design of Small-Molecule Inhibitors of the Hub1 Protein

By binding to the spliceosomal protein Snu66, the human ubiquitin-like protein Hub1 is a modulator of the spliceosome performance and facilitates alternative splicing. Small molecules that bind to Hub1 would be of interest to study the protein-protein interaction of Hub1/Snu66, which is linked to se...

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Detalles Bibliográficos
Autores principales: Reyes Romero, Atilio, Kubica, Katarzyna, Kitel, Radoslaw, Rodríguez, Ismael, Magiera-Mularz, Katarzyna, Dömling, Alexander, Holak, Tad A., Surmiak, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738620/
https://www.ncbi.nlm.nih.gov/pubmed/36500376
http://dx.doi.org/10.3390/molecules27238282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738620/
https://www.ncbi.nlm.nih.gov/pubmed/36500376
http://dx.doi.org/10.3390/molecules27238282

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