The Use of Zidovudine Pharmacophore in Multi-Target-Directed Ligands for AIDS Therapy

The concept of polypharmacology embraces multiple drugs combined in a therapeutic regimen (drug combination or cocktail), fixed dose combinations (FDCs), and a single drug that binds to different targets (multi-target drug). A polypharmacology approach is widely applied in the treatment of acquired...

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Detalles Bibliográficos
Autores principales: Bianco, Maria da Conceição Avelino Dias, Inacio Leite, Debora, Silva Castelo Branco, Frederico, Boechat, Nubia, Uliassi, Elisa, Bolognesi, Maria Laura, Bastos, Monica Macedo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738661/
https://www.ncbi.nlm.nih.gov/pubmed/36500608
http://dx.doi.org/10.3390/molecules27238502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738661/
https://www.ncbi.nlm.nih.gov/pubmed/36500608
http://dx.doi.org/10.3390/molecules27238502

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