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Automated Optimized Synthesis of [(18)F]FLT Using Non-Basic Phase-Transfer Catalyst with Reduced Precursor Amount

3′-deoxy-3′-[(18)F]fluorothymidine ([(18)F]FLT) is a positron emission tomography (PET) tracer useful for tumor proliferation assessment for a number of cancers, particularly in the cases of brain, lung, and breast tumors. At present [(18)F], FLT is commonly prepared by means of the nucleophilic rad...

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Detalles Bibliográficos
Autores principales: Fedorova, Olga S., Orlovskaya, Viktoriya V., Krasikova, Raisa N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738687/
https://www.ncbi.nlm.nih.gov/pubmed/36500417
http://dx.doi.org/10.3390/molecules27238323