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Automated Optimized Synthesis of [(18)F]FLT Using Non-Basic Phase-Transfer Catalyst with Reduced Precursor Amount
3′-deoxy-3′-[(18)F]fluorothymidine ([(18)F]FLT) is a positron emission tomography (PET) tracer useful for tumor proliferation assessment for a number of cancers, particularly in the cases of brain, lung, and breast tumors. At present [(18)F], FLT is commonly prepared by means of the nucleophilic rad...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738687/ https://www.ncbi.nlm.nih.gov/pubmed/36500417 http://dx.doi.org/10.3390/molecules27238323 |