MAGOH and MAGOHB Knockdown in Melanoma Cells Decreases Nonsense-Mediated Decay Activity and Promotes Apoptosis via Upregulation of GADD45A

Cutaneous malignant melanoma is a highly proliferative and aggressive skin cancer with a steadily increasing incidence and a low long-term survival rate after metastatic progression. The protein MAGOH and its highly identical homologue MAGOHB are core components of the exon junction complex (EJC), w...

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Detalles Bibliográficos
Autores principales: Soederberg, Agnes, Meißgeier, Tina, Bosserhoff, Anja Katrin, Linck-Paulus, Lisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738831/
https://www.ncbi.nlm.nih.gov/pubmed/36497117
http://dx.doi.org/10.3390/cells11233859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738831/
https://www.ncbi.nlm.nih.gov/pubmed/36497117
http://dx.doi.org/10.3390/cells11233859

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