Acetyl-CoA Counteracts the Inhibitory Effect of Antiandrogens on Androgen Receptor Signaling in Prostate Cancer Cells

SIMPLE SUMMARY: The androgen receptor (AR) signaling axis is the major therapeutic target in prostate cancer (PC). Second-generation antiandrogens, such as abiraterone acetate and enzalutamide, have shown impressive results in pre- and post-chemotherapy settings, prolonging the survival of PC patien...

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Detalles Bibliográficos
Autores principales: Makhov, Peter, Fazliyeva, Rushaniya, Tufano, Antonio, Uzzo, Robert G., Cai, Kathy Q., Serebriiskii, Ilya, Snyder, Nathaniel W., Andrews, Andrew J., Kolenko, Vladimir M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738902/
https://www.ncbi.nlm.nih.gov/pubmed/36497382
http://dx.doi.org/10.3390/cancers14235900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738902/
https://www.ncbi.nlm.nih.gov/pubmed/36497382
http://dx.doi.org/10.3390/cancers14235900

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