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Computational Analysis Reveals the Temporal Acquisition of Pathway Alterations during the Evolution of Cancer

SIMPLE SUMMARY: Early stage primary cancer, where the tumour has not yet spread from its site of origin, is commonly curable through surgery alone. Conversely, metastatic cancer, where the tumour has disseminated to distant sites, is almost invariably lethal and is the main cause of cancer death. Gi...

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Detalles Bibliográficos
Autores principales: Ahrenfeldt, Johanne, Christensen, Ditte S., Sokač, Mateo, Kisistók, Judit, McGranahan, Nicholas, Birkbak, Nicolai J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739002/
https://www.ncbi.nlm.nih.gov/pubmed/36497297
http://dx.doi.org/10.3390/cancers14235817