Cargando…
TFAM’s Contributions to mtDNA Replication and OXPHOS Biogenesis Are Genetically Separable
The ability of animal orthologs of human mitochondrial transcription factor A (hTFAM) to support the replication of human mitochondrial DNA (hmtDNA) does not follow a simple pattern of phylogenetic closeness or sequence similarity. In particular, TFAM from chickens (Gallus gallus, chTFAM), unlike TF...
Autores principales: | Kozhukhar, Natalya, Alexeyev, Mikhail F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739059/ https://www.ncbi.nlm.nih.gov/pubmed/36497015 http://dx.doi.org/10.3390/cells11233754 |
Ejemplares similares
-
TFAM in mtDNA Homeostasis: Open Questions
por: Alexeyev, Mikhail
Publicado: (2023) -
A Method for In Situ Reverse Genetic Analysis of Proteins Involved mtDNA Replication
por: Kozhukhar, Natalya, et al.
Publicado: (2022) -
35 Years of TFAM Research: Old Protein, New Puzzles
por: Kozhukhar, Natalya, et al.
Publicado: (2023) -
Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos
por: Otten, Auke B. C., et al.
Publicado: (2020) -
Unusual mtDNA Control Region Length Heteroplasmy in the COS-7 Cell Line
por: Kozhukhar, Nataliya, et al.
Publicado: (2020)