Myotoxin-3 from the Pacific Rattlesnake Crotalus oreganus oreganus Venom Is a New Microtubule-Targeting Agent

Microtubule targeting agents (MTA) are anti-cancer molecules that bind tubulin and interfere with the microtubule functions, eventually leading to cell death. In the present study, we used an in vitro microtubule polymerization assay to screen several venom families for the presence of anti-microtub...

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Detalles Bibliográficos
Autores principales: González García, María Cecilia, Radix, Caroline, Villard, Claude, Breuzard, Gilles, Mansuelle, Pascal, Barbier, Pascale, Tsvetkov, Philipp O., De Pomyers, Harold, Gigmes, Didier, Devred, François, Kovacic, Hervé, Mabrouk, Kamel, Luis, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739105/
https://www.ncbi.nlm.nih.gov/pubmed/36500334
http://dx.doi.org/10.3390/molecules27238241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739105/
https://www.ncbi.nlm.nih.gov/pubmed/36500334
http://dx.doi.org/10.3390/molecules27238241

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