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Myotoxin-3 from the Pacific Rattlesnake Crotalus oreganus oreganus Venom Is a New Microtubule-Targeting Agent
Microtubule targeting agents (MTA) are anti-cancer molecules that bind tubulin and interfere with the microtubule functions, eventually leading to cell death. In the present study, we used an in vitro microtubule polymerization assay to screen several venom families for the presence of anti-microtub...
Autores principales: | González García, María Cecilia, Radix, Caroline, Villard, Claude, Breuzard, Gilles, Mansuelle, Pascal, Barbier, Pascale, Tsvetkov, Philipp O., De Pomyers, Harold, Gigmes, Didier, Devred, François, Kovacic, Hervé, Mabrouk, Kamel, Luis, José |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739105/ https://www.ncbi.nlm.nih.gov/pubmed/36500334 http://dx.doi.org/10.3390/molecules27238241 |
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