The Mechanism of Selective Recognition of Lipid Substrate by hDHHC20 Enzyme

S-acylation is a post-translational linkage of long chain fatty acids to cysteines, playing a key role in normal physiology and disease. In human cells, the reaction is catalyzed by a family of 23 membrane DHHC-acyltransferases (carrying an Asp-His-His-Cys catalytic motif) in two stages: (1) acyl-Co...

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Detalles Bibliográficos
Autores principales: Panina, Irina S., Krylov, Nikolay A., Chugunov, Anton O., Efremov, Roman G., Kordyukova, Larisa V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739150/
https://www.ncbi.nlm.nih.gov/pubmed/36499114
http://dx.doi.org/10.3390/ijms232314791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739150/
https://www.ncbi.nlm.nih.gov/pubmed/36499114
http://dx.doi.org/10.3390/ijms232314791

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