Direct Cardiac Epigenetic Reprogramming through Codelivery of 5′Azacytidine and miR-133a Nanoformulation

Direct reprogramming of cardiac fibroblasts to induced cardiomyocytes (iCMs) is a promising approach to cardiac regeneration. However, the low yield of reprogrammed cells and the underlying epigenetic barriers limit its potential. Epigenetic control of gene regulation is a primary factor in maintain...

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Detalles Bibliográficos
Autores principales: Muniyandi, Priyadharshni, Palaninathan, Vivekanandan, Hanajiri, Tatsuro, Maekawa, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739153/
https://www.ncbi.nlm.nih.gov/pubmed/36499508
http://dx.doi.org/10.3390/ijms232315179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739153/
https://www.ncbi.nlm.nih.gov/pubmed/36499508
http://dx.doi.org/10.3390/ijms232315179

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