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Direct Cardiac Epigenetic Reprogramming through Codelivery of 5′Azacytidine and miR-133a Nanoformulation
Direct reprogramming of cardiac fibroblasts to induced cardiomyocytes (iCMs) is a promising approach to cardiac regeneration. However, the low yield of reprogrammed cells and the underlying epigenetic barriers limit its potential. Epigenetic control of gene regulation is a primary factor in maintain...
Autores principales: | Muniyandi, Priyadharshni, Palaninathan, Vivekanandan, Hanajiri, Tatsuro, Maekawa, Toru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739153/ https://www.ncbi.nlm.nih.gov/pubmed/36499508 http://dx.doi.org/10.3390/ijms232315179 |
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