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Adamantane-Substituted Purine Nucleosides: Synthesis, Host–Guest Complexes with β-Cyclodextrin and Biological Activity

Purine nucleosides represent an interesting group of nitrogen heterocycles, showing a wide range of biological effects. In this study, we designed and synthesized a series of 6,9-disubstituted and 2,6,9-trisubstituted purine ribonucleosides via consecutive nucleophilic aromatic substitution, glycosy...

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Detalles Bibliográficos
Autores principales: Rudolfová, Jana, Kryštof, Vladimír, Nečas, Marek, Vícha, Robert, Rouchal, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739181/
https://www.ncbi.nlm.nih.gov/pubmed/36499470
http://dx.doi.org/10.3390/ijms232315143